Stress-Induced Down-Regulation of CPEB4 Disrupts Sodium Channel Regulation and Myocardial Excitability
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Unstable ion channel mRNAs contribute to electrical remodeling and arrhythmic risk in heart failure. CPEB4 promotes cytoplasmic polyadenylation and stabilizes target mRNAs, thereby supporting translation. CPEB4 expression was reduced in human heart failure and... ...
