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Mechanisms Underlying the Waning of Osteoanabolic Therapy Effects in Osteoporosis

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Osteoanabolic therapies such as parathyroid hormone (PTH) analogs (teriparatide, abaloparatide) and the sclerostin inhibitor romosozumab rapidly stimulate new bone deposition but their bone-building effects are not indefinite. Clinical trials including bone tu... ...