Surface-bioengineering of bacteriophage AP205 and MS2 virus-like particles with novel Spytag003 for antigen conjugation
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The insertion of foreign antigens on the coat protein of viruses sometimes interferes with the ability of the coat proteins to assemble into virus-like particles (VLPs). To overcome this limitation, Spytag/Spycatcher bio-conjugation system was developed; howev... ...