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Development of injectable ibuprofen and resveratrol co-loaded mesoporous silica nanoparticle-based hydrogels for sustained delivery in osteoarthritis management

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This study reports the synthesis of mesoporous silica nanoparticles (MSNs), MCM‑41 (M41) and SBA‑15 (S15), individually loaded with ibuprofen (M41IF, S15IF) and resveratrol (M41RS, S15RS). These drug‑loaded MSNs were formulated into thermoresponsive injecta... ...