TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis
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Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron degeneration and cytoplasmic mislocalization of TDP-43. While metabolic dysfunction is increasingly recognized in ALS, the mechanistic link betw... ...
