Development and Validation of Reverse Phase High-Performance Liquid Chromatographic Method Enabling Simultaneous Estimation of Polmacoxib and its Process-Related Impurities: Exploring Degradation Pathways and Elucidating Degradant Structures via LC-MS/MS and NMR Spectroscopy
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A simple, sensitive, and selective reverse phase high-performance liquid chromatography (HPLC) method was developed and validated for the estimation of Polmacoxib (POL) and its process-related impurities. Chromatographic separation was achieved on a Kromasil C... ...
