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Role of Dissolution Medium pH in the Release Behavior of Basic Drug-Copovidone Amorphous Solid Dispersions

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Amorphous solid dispersions (ASDs) are one of the most effective formulation strategies for improving the release rate and bioavailability of poorly water-soluble drugs. However, the release rates of polyvinylpyrrolidone vinyl acetate (PVPVA) based ASDs typica... ...