A multimodal neoadjuvant strategy incorporating PDT, RFA, and ICIs results in a notable pathological response and preservation of the sphincter in microsatellite stable low rectal cancer: A highly distinctive case report and literature review
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Microsatellite stable (MSS) rectal cancer generally shows limited response to immunotherapy because of its low tumor mutational burden and immunosuppressive tumor microenvironment. Meanwhile, locally advanced low rectal cancer presents a major clinical challen... ...
