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Impaired retinoic acid receptor-γ signalling underlies a heritable form of urothelial keratinising squamous metaplasia

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Keratinising desquamative squamous metaplasia (KDSM) of the urinary tract is typically a sporadic condition with unclear aetiology and treatment options. It is characterised by either a focal or widespread transition of normal urothelium of the bladder and ure... ...