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Development and Preliminary Evaluations of a Novel 18F-Labeled Tracer for Detection of BRAFV600E Mutant Status in Animal Models of Melanoma

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The BRAFV600E mutation is a well-established oncogenic driver, and several oral inhibitors have achieved clinical success. However, radiolabeled tracers for the non-invasive imaging of this mutation remain limited. N-(2-Chloro-3-((3,5-dimethyl-4-oxo-3,4-dihydr... ...