Design, synthesis, and biological evaluation of small-molecule HMGB1 inhibitors for the alleviation of radiation-induced skin injury
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Radiation-induced skin injury (RSI) is a common and debilitating complication of radiotherapy, significantly impairing patients' quality of life. High-Mobility Group Box 1 (HMGB1), a key damage-associated molecular pattern (DAMP) protein, plays a critical rol... ...
