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Humupulusones A and B, Two Skeletally Novel Acylphloroglucinol Derivatives from Humulus lupulus

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Two novel acylphloroglucinol derivatives, humupulusones A and B (1 and 2), were isolated from Humulus lupulus. Compound 1, a pair of enantiomers (1a/1b), is the first acylphloroglucinol derivative with a bicyclo[2.2.2] carbon skeleton possessing a novel 5/6/6/... ...