Bisarylthiourea comprising cycloalkyl-thiophene-3-carboxylate derivatives as potential human toll-like receptor (TLR2) agonists: design, synthesis, and structure-activity relationship enabling the switch from TLR2/1 to TLR2/6 activation
{{output}}
Toll-like receptor 2 (TLR2) acts as a pivotal family of pattern-recognition receptors that bridges innate and adaptive immunity through the detection of PAMPs and DAMPs. In pursuit of novel immunomodulators, a series of bisarylthiourea (BAT) comprising cycloal... ...
