Reduction of calreticulin and ERp57 with age reveals the ER stress-related roles in cell viability and organismal lifespan regulation
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Introduction: Defects in Calreticulin (Calr) and ER protein 57 (ERp57), two tandem endoplasmic reticulum (ER) resident proteins, are associated with pathologies ranging from protein conformational disorders to impaired immune res... ...
