IGF-1 from bone marrow Adipoq-lineage cells stimulates endocortical bone formation in mature female mice
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Insulin-like growth factor 1 (IGF-1) is an anabolic signal promoting growth, differentiation and function of both embryonic and postnatal tissues. Both endocrine and paracrine functions of IGF-1 have been documented to regulate bone growth and BM hematopoiesis... ...