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Pediatric high-grade gliomas, H3-wildtype, IDH-wildtype: Refining diagnostic criteria and exploring clinical associations

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Background: Diffuse pediatric-type high-grade gliomas (pHGGs), H3-wildtype (H3 WT), and IDH-wildtype (IDH WT), represent a newly recognized, highly malignant brain tumor entity with unique molecular and epigenetic profiles. Despi... ...