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αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative Breast Cancer

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One of the many barriers to successful chimeric antigen receptor (CAR) T-cell immunotherapy against solid tumors is the scarcity of targetable molecules common to multiple types of cancer. The purpose of this study was to determine the efficacy of αvβ3 CAR-T... ...