Peptidyl keto vinyl amides as improved inhibitors of cathepsin L
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Cysteine protease cathepsin L (CatL) is linked to cancer, infection, and neurodegeneration, rendering it a compelling target for therapy. Expanding upon dipeptidyl enoates (keto vinyl esters, KVE), we introduce dipeptidyl keto vinyl amides (KVA) as a more stab... ...
