IgE-dependent anaphylaxis is regulated by sphingolipid binding to activating and inhibitory CD300 family members
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Immunoglobulin E (IgE)-dependent mast cell degranulation and anaphylaxis are suppressed by the CD300f-ceramide interaction. However, the related, positive regulatory mechanisms remain unclear. Here, we examine the effect of FcεRIγ-coupled CD300d3 on IgE-depe... ...
