S5D mutation of NLRP3 revealed its role in NLRP3 inflammasome complex using split-luciferase complementation assay
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The NOD-like receptor (NLR) family pyrin domain-containing protein 3 (NLRP3) is a critical cytosolic inflammasome sensor of exogenous and endogenous danger signals and is a highly attractive medicinal target against inflammatory diseases. The molecular mechani... ...
