Endothelin-1 upregulates cyclooxygenase-2 expression and prostaglandin E2 synthesis in human periodontal ligament cells-an in vitro study
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Aims: Endothelin-1 (ET-1) increased bone resorption during orthodontic tooth movement (OTM) in animal models, suggesting potential clinical applications for accelerating OTM. However, the molecular mechanisms by which ET-1 regula... ...
