Potentiating Antibody-Dependent Cell-Mediated Cytotoxicity via Tumor-Specific Anchoring and Activation of Nano-Haptens
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Tumor-surface antigen deficiency and immunosuppressive tumor microenvironment (TME) hurdle the efficacy of antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells. Here, acid-activatable, polypeptide-based nano-haptens are develop... ...