LncRNA LASTR promotes TGF-β signalling and EMT in HNSCC by enhancing TGFβR1 expression by suppressing biogenesis of miR-34a and acting as its ceRNA
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Head and Neck Squamous Cell Carcinomas (HNSCC) are a heterogeneous collection of malignancies of the head and neck region. Transforming growth factor beta (TGF-β)-regulated long non-coding RNAs (lncRNAs) modulate several aspects of tumor development, includin... ...