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Neuroprotective Effects of Esketamine in Central Nervous System Disorders: Mechanisms and Cellular Targets

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Esketamine (ESK), the dextrorotatory enantiomer of ketamine, is an antagonist of the N-methyl-D-aspartic acid (NMDA) receptor. ESK is considered an effective anesthetic because of its ability to mitigate postoperative pain and opioid use. Recently, it has attr... ...