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The effect of mitoTEMPO on the development of hypoxia-induced pulmonary hypertension in male mice

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Mitochondrial reactive oxygen species (mtROS) have been implicated in the development of chronic hypoxia-induced pulmonary hypertension (PH), potentially through hypoxia-inducible factor-1α (HIF-1α) stabilization. However, the role of mtROS in HIF-1α stabil... ...