Enantioselective Copper-Catalyzed Synthesis of Hydroxylamines via Hydrofunctionalization of Alkenes using Nitroalkanes
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Herein, we report that nitroalkanes are competent electrophiles for the enantioselective copper hydride (CuH)-catalyzed alkene hydrofunctionalization of vinyl(hetero)arenes to generate hydroxylamines in good yields and with high levels of enantioselectivity. C... ...