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Intestinal stearoyl-CoA desaturase-2 is highly expressed and nutritionally regulated but dispensable for energy balance

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The stearoyl-CoA desaturase (SCD) enzymes convert saturated fatty acids to monounsaturated fatty acids (MUFAs). Deletion of intestinal SCD1 confers metabolic benefits upon high-fat diet (HFD) feeding. We report here that mice express a second SCD isoform in th... ...