Beyond tumor mutational burden: a framework for immune-checkpoint blockade responsiveness in gastrointestinal cancers
{{output}}
Immune-checkpoint blockade (ICB) elicits profound and durable responses in mismatch repair-deficient (dMMR) or microsatellite instability-high (MSI-H) gastrointestinal (GI) cancers, yet most microsatellite-stable (MSS) cancers derive minimal benefit. This gap ... ...
