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Synthesis of β-aminoacrylated betulin derivatives by a spontaneous amino-yne reaction for antifungal applications

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Betulin, a lupane-based pentacyclic triterpenoid, is renowned for its sustainability and potent antifungal properties. By leveraging a spontaneous amino-yne reaction in conjunction with betulin, novel biomolecules representing a diverse library of triterpenoid... ...