Persistent spatial immune responses in glioblastoma following oncolytic virus therapy
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Glioblastoma (GBM) remains highly resistant to immunotherapy due to limited T-cell infiltration and a profound immunosuppressive tumor microenvironment (TME). A recent first-in-human clinical trial of the oncolytic herpes simplex virus rQNestin34.5 v.2 (NCT031... ...
