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Extracellular ATP induces the proinflammatory phenotype transition of MH7A cells by activating P2X7 receptor

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The transition of fibroblast-like synoviocytes (FLS) toward a proinflammatory phenotype is a hallmark of rheumatoid arthritis (RA), with proinflammatory RA-FLS exacerbating joint destruction via hyperproliferation, enhanced migration/invasion, and excessive in... ...