NEUTROPHIL INFLAMMASOME ACTIVATION AND PYROPTOSIS INDUCED BY A METALLOPROTEINASE VIA HIF-1α AND GASDERMIN D PATHWAYS
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Bothrops jararacussu venom contains snake venom metalloproteinases (SVMPs) that contribute to inflammation and tissue damage. BjussuMP-II, a PI-class SVMP, lacks hemorrhagic activity but retains proteolytic and immunomodulatory properties. Here, we uncover a p... ...
