Aurora B kinase phosphorylates keratin 8 at the cleavage furrow to drive spatially restricted intermediate filament disassembly during cytokinesis
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Keratins form intermediate filament networks that stabilize epithelial cells and many cancer cells. During cytokinesis, these filaments must be locally disassembled at the cleavage furrow to allow furrow ingression and cell separation. In this issue, Harmanda ... ...
