One-Pot O-Glycan Release and Permethylation (OPORP) Enables Rapid and Quantitative O-Glycan Analysis from Low-Input Samples
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O-glycosylation, an exceptionally complex and heterogeneous post-translational modification, plays pivotal roles in diverse biological and pathological processes, and is a key regulator of biopharmaceutical quality and efficacy. However, the vast structural di... ...