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Investigation of alternative cell models to BALB/c 3T3 for in vitro neutral red uptake phototoxicity test of pharmaceuticals: NIH 3T3 and HaCaT cells

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Phototoxicity assessment is a critical component of preclinical safety assessment of pharmaceuticals with potential photosensitivity. 3T3 Neutral Red Uptake (NRU) Phototoxicity test, OECD Test Guideline 432, has been widely used as a reference method but conce... ...