Dissecting the role of imiquimod and isostearic acid in Aldara-induced psoriasis mouse model
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Aldara (5% imiquimod with 25% isostearic acid [ISA]) cream-induced psoriasiform inflammation is a widely used mouse model to study psoriasis. Imiquimod is a toll-like receptor 7 (TLR7) agonist; however, the role of TLR7 signaling in human psoriasis is unclear.... ...