Alternatively-spliced STIM2.3 is an evolutionary late Store-operated Calcium Entry regulator expressed in brain
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Ca2+ homeostasis is essential for cellular functions, with regulation by Store-Operated Ca2+ Entry (SOCE) omnipresent. Due to a reduced ER-luminal Ca2+ affinity, STIM2 regulates basal cytosolic Ca2+ but also increases interaction and activation of ORAI protein... ...
