Desymmetrization and Atroposelective Cobalt Catalyzed C-H Annulation of Phosphinic Amides with Ynamides
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Metal-catalyzed asymmetric C-H annulation enables enantioselective synthesis from simple precursors, but methods that simultaneously generate multiple stereogenic elements in a single step remain rare. We report the first Co(II)/Salox-catalyzed desymmetrizing ... ...
