RNase L regulates the antiviral proteome by accelerating mRNA decay, inhibiting nuclear mRNA export, and repressing transcription
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Ribonuclease L (RNase L) is an antiviral endoribonuclease that triggers widespread degradation of cellular mRNAs. Here, we show that RNase L-mediated decay of cellular mRNA is a conserved response to flaviviruses, including Zika virus (ZIKV), dengue virus sero... ...
