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Preclinical assessment of leukocyte- and platelet-rich fibrin for inhibition of mandibular osteonecrosis

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Considering that osteonecrosis of the jaw may be due to the antiangiogenic effect of bisphosphonates and that leukocyte- and platelet-rich fibrin (L-PRF) releases proangiogenic factors, this study hypothesized that L-PRF could prevent mandibular osteonecrosis ... ...