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Loss of NF-κB inducing Kinase (NIK) affects eosinophilopoiesis in a murine model of Hypereosinophilic Syndrome

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NF-κB inducing kinase (NIK), an upstream regulator of the noncanonical NF-κB signaling pathway, is implicated in the development of Hypereosinophilic-like syndrome (HES) in mice. HES in human patients is defined by 1.5x109 cells/L circulating in the blood wi... ...