Synthesis of Antimicrobial Quinoline Derivatives Enabled by Synergistic Pd/Enamine Catalysis: Experimental and Computational Study
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An intermolecular addition of acetophenone derivatives to unactivated alkenes was developed through Pd-(II)/amine cooperative catalysis. This dual catalytic system functions by activating the amide-containing alkene via Pd-(II) coordination while simultaneousl... ...
