Simple Fed-Batch Strategy for Production of Capsular Polysaccharide by Haemophilus influenzae b at Pilot Scale
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Haemophilus influenzae b (Hib) is a pathogenic bacterium that causes meningitis worldwide, mainly in children less than two years old. The capsular polysaccharide b (PRP) is an essential antigen for vaccine formulation. This study aimed to develop a high-yield... ...