Toll-like Receptor 3 is Required for Sensing Extracellular Double Stranded RNA in Salmonid Cells
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The membrane-bound toll-like receptor 3 (TLR3) binds to double-stranded RNA (dsRNA) derived from viruses, as well as poly(I: C), its synthetic analogue. Upon dsRNA binding, TRIF is recruited to the TLR3 dimer and leads to the activation of the transcription fa... ...
