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Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells

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Shikonin has been reported to regulate caudal-type homeobox 2 (CDX2)-mediated intestinal epithelial cell (IEC) differentiation, and ferroptosis has been identified a critical event during this process. However, the exact role of ferroptosis in shikonin-induced... ...