Response Factor Correction for Quantitative Determination of Homooligomeric Sso SSB Binding to ssDNA by Native Mass Spectrometry
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Native mass spectrometry (nMS) has emerged as a complementary approach for elucidating molecular parameters of biological complexes relative to solution-phase experiments. Herein, we utilize nMS to determine the subunit binding affinities (Kd,i) of the single-... ...