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Preventing COVID-19 in at-risk populations: moving towards next-generation mRNA-1283 COVID-19 vaccine to address current challenges

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Introduction: Next-generation COVID-19 vaccines hold promise to reduce severe outcomes in populations most at risk. While the original mRNA COVID-19 vaccine, mRNA-1273, targets the full-length SARS-CoV-2 spike protein, mRNA-1283 ... ...