Similarity of the ion occupations of K+ and Tl+ in the selectivity filter of a K+ channel, as verified by single-channel currents
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Voltage-dependent gating in the selectivity filter of potassium channels is modulated by the permeating ions binding within the filter. In the viral Kcv channel, filter gating occurs on the sub-millisecond time scale. Crystallographic data from KcsA in the lit... ...
