Inhibiting AP2M1-mediated GluA2 endocytosis by G2CT peptide ameliorates synaptic and memory deficits in Alzheimer's Disease
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Abnormal endocytosis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) subunit GluA2 is implicated in early synaptic dysfunction in Alzheimer's disease (AD). In this study, we utilized human brain tissue samples from both male and fe... ...
