Mechanistic dermal patch modelling for fentanyl: Linking in vitro release and permeation data to a physiologically based pharmacokinetic approach
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Dermal physiologically based pharmacokinetic (PBPK) models can be informed by various types of data. In vitro permeation testing (IVPT) experiments aid parameterisation of skin permeation independent of the complexities of systemic uptake. In vitro release tes... ...
